Hot flashes?
Give ‘em the mist.

Evamist^® is the only adjustable dosing spray to help relieve moderate-to-severe hot flashes due to menopause.¹

Estrogens with or without progestins should be used with the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman.

COPAY SAVINGS OPTIONS HOW EVAMIST® WORKS

Find Relief from Menopause Hot Flashes with Evamist®

Experiencing moderate-to-severe hot flashes due to menopause?

Find targeted relief with Evamist^® (estradiol transdermal spray), the only FDA-approved estrogen therapy spray² clinically proven to reduce both the frequency and severity of hot flashes.² Discover how this once-daily, flexible-dose treatment delivers estrogen directly through the skin to help you manage your symptoms effectively.

DISCOVER THE DIFFERENCE EVAMIST® SAVINGS PROGRAM

Explore Your Treatment Journey

What Are Hot Flashes?

Unpredictable warmth, flushing, and night sweats can disrupt your daily life.² Learn the biology behind menopause-related hot flashes and how estrogen therapy targets the root cause.

HOT FLASHES 101 >

How Evamist^® Works

Evamist^®delivers estrogen directly through the skin into your bloodstream with a simple, once-daily spray.² See how easily it fits into your daily routine by viewing our step-by-step guide.

WATCH IT IN ACTION >

Patient Resources

Access helpful tools to support your treatment. Find downloadable brochures, informative videos, and answers to Frequently Asked Questions (FAQs) all in one convenient place.

EXPLORE RESOURCES >

Evamist^® offers the most titration choices for a single hormone replacement therapy (HRT) prescription.

Dosing built around you

An applicator that provides the flexibility of 3 daily dosing options
Enables women to start with the lowest dose and titrate according to their healthcare provider’s direction
- Use of estrogen alone, or in combination with a progestin, should be with the lowest effective dose and the shortest duration consistent with treatment goals and risks for the individual woman

Convenience and precision

Dries quickly with no messy residue³
Let dry for at least 2 minutes before covering skin with clothing
Refrain from washing skin for at least an hour
Women should ensure that children do not come into contact with the site(s) where Evamist^® (estradiol transdermal spray) is applied

Young children who are accidentally exposed to estrogen through contact with women using Evamist^® (estradiol transdermal spray) may show signs of puberty that are not expected (e.g., breast budding, breast masses, and gynecomastia). In most cases, the condition resolved with removal of Evamist^® exposure. Women should ensure that children do not come into contact with the site(s) where Evamist^® is applied.²

2 Ways to Save on Your Evamist® Prescription

If you want to reduce your out-of-pocket costs, consider these options:

1. Padagis^® Savings Program:

PAY AS LITTLE AS $25*

Commercial & Cash Paying Patients save up to $70. Download our coupon to see program details and terms and conditions.

DOWNLOAD COUPON

2. GoodRx^® Coupon:

Purchase one bottle of Evamist^® estradiol spray for an exclusive, discounted price at major participating pharmacies. Click the button below to see your GoodRx^® savings.

SEE GOODRX® SAVINGS

References:

FDA Orange Book (Approved Drug Products with Therapeutic Equivalence Evaluations) https://www.fda.gov
Evamist® (estradiol transdermal spray) Prescribing Information, Padagis, October 2024
Data on file, Padagis

Important Safety Information for EVAMIST® (estradiol transdermal spray)

What is the most Important Information I should know about EVAMIST (an estrogen hormone)?

Using estrogen-alone may increase your chance of getting cancer of the uterus (womb).
Report any unusual vaginal bleeding right away while you are using EVAMIST. Vaginal bleeding after menopause may be a warning sign of cancer of the womb.
Do not use estrogen alone or with progestins to prevent heart disease, heart attacks, strokes or dementia (decline in brain function).
Using estrogen-alone or with progestins may increase your chances of getting strokes, blood clots, or dementia.
Using estrogens with progestins may increase your chances of getting heart attacks or breast cancer.
The estrogen in EVAMIST spray can transfer from the area of skin where it was sprayed to other people. Do not allow others, especially children, to come into contact with the area of your skin where you sprayed EVAMIST. Young children who are accidentally exposed to estrogen through contact with women using EVAMIST may show signs of puberty that are not expected (for example, breast budding).
You and your healthcare provider should talk regularly about whether you still need treatment with EVAMIST.

Do not start using EVAMIST if you have unusual vaginal bleeding; have been diagnosed with a bleeding disorder; currently have or have had certain cancers; had a stroke or heart attack; currently have or have had blood clots; currently have or have had liver problems; are allergic to EVAMIST or any of its ingredients

Before you use EVAMIST, tell your healthcare provider if you have any unusual vaginal bleeding; have any other medical conditions; are going to have surgery or will be on bed rest; are pregnant or think you may be pregnant; or are breast feeding

Tell your healthcare provider about all medicines you take. Some medicines may affect how EVAMIST works. EVAMIST may also affect how your other medicines work.

Talk to your healthcare provider about other treatments for your menopause symptoms if accidental exposure to EVAMIST cannot be avoided.

EVAMIST contains alcohol, which is flammable. Avoid fire, flame, or smoking until the area of your skin where you have applied EVAMIST has dried.

The most common side effects associated with EVAMIST are headache, breast tenderness, nipple pain, back pain and nasopharyngitis.

These are not all the possible side effects of EVAMIST. For more information, refer to the Patient Information section of the full Prescribing Information or ask your healthcare provider or pharmacist.

For more information about Evamist, contact Customer Service at 1-866-634-9120, Monday-Friday, 8:00 am-5:00 pm (EST).

Healthcare professionals and patients with inquiries or adverse event reports, please call 1-866-634-9120.

About Padagis

Privacy Policy

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

The information on this Web site should not take the place of talking with your doctor or healthcare professional. If you have any questions about your condition, or if you would like more information about Evamist, talk to your doctor or pharmacist. Only you and your healthcare professional can decide if Evamist^® (estradiol transdermal spray) is right for you.

Hot flashes? Give ‘em the mist.

Evamist® is the only adjustable dosing spray to help relieve moderate-to-severe hot flashes due to menopause.¹