Each Evamist® (estradiol transdermal spray) applicator contains enough medication to allow for initial priming of the pump with 3 sprays and application of 56 sprays, providing the precise amount of medicine each time the applicator is used.
The product will last approximately 56 days if you use 1 spray each day, 28 days if you use 2 sprays each day, and 18 days if you use 3 sprays each day. Do not use this applicator for more than 56 sprays even though the bottle may not be completely empty.
Click the video to view instructions on every day dosing with Evamist®.
Steps to applying Evamist.
Before using the Evamist® (estradiol transdermal spray) applicator for the first time, it must be primed. With the cover on and the applicator upright, fully depress the applicator 3 times with your thumb or index finger. After priming, the applicator is ready to use. DO NOT PRIME THE APPLICATOR BEFORE EACH DAY’S DOSE.
Do not apply Evamist® (estradiol transdermal spray) to other areas of the skin. Never apply Evamist directly to the breast or in or around the vagina.
Take steps to avoid unintended exposure to estrogen.
After you spray Evamist® (estradiol transdermal spray) on your skin, do not allow other people and pets to make contact with the area of skin where you applied the spray after application. Cover your skin with clothing where you sprayed Evamist if you think another person will come in contact with that area of skin. If you get Evamist spray on another area of your skin like your hands, wash that area of your skin with soap and water right away.
The estrogen in Evamist® (estradiol transdermal spray) can transfer from the area of skin where it was sprayed to other people. Do not allow others, especially children, to come into contact with the area of your skin where you sprayed Evamist. Young children who are accidentally exposed to estrogen through contact with women using Evamist may show signs of puberty that are not expected (for example, breast budding).
If another person accidentally touches the area of your skin where you sprayed Evamist® (estradiol transdermal spray), tell that person to wash the area of their skin with soap and water right away. The longer Evamist stays on the skin before it is washed off, the greater the chance the estrogen hormone may be absorbed.
If a child under your care unexpectedly starts to develop breasts or has other sexual changes:
- Have the child checked right away by their healthcare provider
- Stop using Evamist® (estradiol transdermal spray) and call your healthcare provider right away if you see any signs and symptoms in a child that may have occurred through accidental exposure to Evamist. In most cases the child’s breasts will go back to normal when they are no longer exposed to Evamist.
- Talk to your healthcare provider about the correct use of Evamist when around children
- Talk to your healthcare provider to discuss other treatments for your menopause symptoms if accidental exposure to Evamist cannot be avoided
Evamist® (estradiol transdermal spray) contains alcohol, and alcohol-based liquids are flammable. Avoid fire, flame, or smoking when using Evamist until the spray has dried. Do not apply Evamist while standing near a flame.
Evamist® (estradiol transdermal spray) can be stored in a clean, dry place at room temperature (15° to 30°C or 59° to 86°F) and does not need refrigeration. Do not freeze.
Evamist® (estradiol transdermal spray) should not be used after the expiration date.